Oral insulin not effective in preventing type 1 diabetes - Author Abstract

AORN Journal,  Oct, 2003  

• E-mail
• Print
• Link

Oral insulin intake does not delay or prevent type 1 diabetes in people at moderate risk for developing the disease within five years, according to a June 15, 2003, news re[ease from the National Institutes of Health. Three hundred seventy-two people participated in a trial that compared the rate of type 1 diabetes progression among those who took a daily capsule of insulin crystals and those who took a placebo. All participants had a 25% to 50% chance of developing type 1 diabetes within 5 years based on results of genetic, immunologic, and metabolic tests. After an average of 4.3 years, approximately 35% of the participants developed type 1 diabetes in each group.

This oral insulin trial is the third Large study that has failed to prevent type I diabetes in at-risk people. The other trials have tested the effects of low-dose insulin injections and nicotinamide, a vitamin present in small amounts in a normal diet.

Oral Insulin Does Not Prevent Type 1 Diabetes (news release, Bethesda, Md: National Institutes of Health, June 25, 2003) http://www.nih.gov/news/pr/jun2003/niddk-15.htm (accessed 17 June 2003).

COPYRIGHT 2003 Association of Operating Room Nurses, Inc.
COPYRIGHT 2003 Gale Group